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Endometriosis and epithelial ovarian cancer: a two-sample Mendelian randomization analysis

Beyond, many of the observed changes occurred in patients with BD can be considered as signs of premature aging (telomere length, oxidative stress, inflammation, disruptions on biological clocks, epigenetic aging and mitochondrial dysfunction), as prior works hypothesize that accelerated aging process is potentially implicated in the development and course of BD [52]

But its a promising start.

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Two clinical trials, FIGARO-DKD [53] and FIDELIO-DKD [54], investigated the impact of a novel non-steroidal mineralocorticoid receptor antagonist called finerenone on patients with both diabetes and CKD