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In most cases, these side effects should be temporary

[DOI] [PMC free article] [PubMed] [Google Scholar] 37.Kilarkaje N., Yousif M.H., El-Hashim A.Z., Makki B., Akhtar S., Benter I.F

Exercise, on the other hand, complements the weight loss effects of semaglutide and tirzepatide by increasing calorie burn and building lean muscle mass

[1] Additionally, patients with pre-existing GERD, hiatal hernia, or Barrett's esophagus should inform their healthcare provider before starting tirzepatide, as closer monitoring may be appropriate

[8] [9] Women should be counseled about the possibility of restored fertility with weight loss