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Akkermansia P9 protein and Clostridium butyricum butyrate both stimulate pathways that enhance GLP-1 signaling, which should complement semaglutide effects

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Results As shown in Table 1, 780 patients (49.6% male) were enrolled, 224 of which had type 1 DM (T1DM) and the others had type 2 DM (T2DM), with the following features: age 62 15 years, BMI 29 6 kg/m 2 , disease duration 18 11 years, daily insulin dose 46 26 IU, and daily insulin injections 3.7 2.6