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For the BTX-A + GLP-1RA cohort, the index event was the earliest date on which patients concurrently met the criteria for overactive bladder, BTX-A injection, and an active GLP-1 receptor agonist prescription (semaglutide or analogues)

Patient-level considerations Clinicians considering GLP-1 RAs for patients with suboptimally controlled hypertension should be mindful of existing antihypertensive therapy

Extracellular aggregates of A amyloid protein and phosphorylated tau protein are common pathological deposits in the brains of Alzheimers patients