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Holst, 2022)
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In addition, the insulinotropic effect of the dual GIP/GLP-1 receptor agonist was abrogated by GIP receptor antagonist (GIPRA) in GLP-1R null mice (63)

This puts you at greater risk of illness, decreases quality of life, and makes weight loss harder to maintain

The Role of GLP-1 in Blood Sugar Regulation GLP-1 (Glucagon-Like Peptide-1) is a natural hormone that: Stimulates insulin release Slows digestion Reduces appetite GLP-1 receptor agonists mimic this hormone, leading to better blood sugar control and weight reduction