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Description
[ 31 , 32 ] OGlcNAcylation, a modification driven by the hexosamine biosynthetic pathway (HBP), uses UDPGlcNAc synthesized from extracellular glucose
A patient can lose pounds while also losing lean mass and drifting into nutritional deficiency
The pathophysiology is unclear, but risk factors are thought to be the same as the type 1 diabetic patients who rapidly improved A1c in the Diabetes Control and Complications Trial: long duration of diabetes mellitus, long duration of poor glycemic control, worse baseline level of DR prior to treatment and magnitude of reduction in A1c after treatment
Targets Fat Loss
We Know Where New Weight Loss Drugs Came From, but Not Why They Work. Novo Nordisk
