glp 1 causing acne GLP-1 Medications and Acne: Research Insights for Australia & NZ Exploring the Impact of Tirzepatide

While GLP-1s reduce fat, they don't always fix cellulite

Clinical trials (ten studies, 419 participants) using doses from 400 mg to 10 g over 21 days to 20 months show consistent reductions in fasting glucose, post-meal glucose, and HbA1c. In diabetic animal studies, gymnema increased proglucagon gene expression (a precursor for GLP-1) and insulin gene activity, suggesting it may help amplify endogenous GLP-1 production

If youve been on social media or watched the news lately, youve heard of GLP-1s

This Topic Guide brings together everything Peter has discussed across podcasts, AMAs, and writing to help you understand how GLP-1 agonists work, what the evidence actually shows, and how to reason clearly about their roleif anyin a sustainable, long-term approach to health.

Given the promising results in pre-clinical models (even in the absence of T2D), a unique mechanism of action and multiple age-related reduced disease risks that have been reported with acarbose, support for clinical trials with acarbose focusing on aging-related outcomes and incorporating biological sex, age at treatment initiation, and T2D-dependence within the design is warranted.