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GLP-1 RAs provide sustained central and peripheral GLP-1R activation that blunts appetite via hypothalamusvagusNTS circuits, improves metabolic health, and may reduce alcohol and other substance-related craving and reward signals.

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According to PharmaTrac data., Mounjaro launched in March last year, added Rs.105 crore in December, taking its total sales to Rs.600 crore in sales, reflecting rapid uptake despite hardly any insurance coverage and outofpocket affordability constraints.

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