glp-1 discovery Xenopus GLP-1-inspired of novel receptor agonists as long-acting hypoglycemic and insulinotropic agents with significant therapeutic potential Evolution of GLP-1 receptor agonists
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Obesity with Type 2 Diabetes 10.2.2

Clinical data also indicate beneficial molecular effects of GLP-1 RAs, despite their potential to reduce muscle mass

Alterations on the delivery of nutrients to the small intestine resulting from the fundoplication, which decreases the accommodating capacity of the stomach, may explain the rapid rise in glucose and enhanced GLP-1 release

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