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While these outcomes are based on large clinical trials (STEP 1 and SURMOUNT-1), weight loss should still be approached with realistic expectations, personalized goals, and ongoing support

[DOI] [PubMed] [Google Scholar] 82.Yusta B, et al

Patients should be advised that initial shedding may occur in the first few weeks, and visible improvement typically takes 36 months of consistent use

Taken together, the evidence is clear: microdoses of GLP-1 paired with microhabits can unlock outsized health benefits

By improving insulin sensitivity and reducing excess adipose tissue, GLP-1s may indirectly decrease estrogen-driven inflammation for some patients