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Every time you sit down for a meal, special cells lining your intestines kick into gear and pump out GLP-1

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This gives each skin area several weeks to fully recover before another patch is applied there
Chandra S, Radwan MM, Majumdar CG, Church JC, Freeman TP, ElSohly MA

In contrast, long-acting agents appear to have a larger effect on lowering fasting glucose due to their effect to increase insulin release and inhibit glucagon release (Meier 2012)