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Strong research suggests that obesity management can delay the progression of prediabetes to type 2 diabetes and facilitate the treatment of type 2 diabetes [1315]

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10.2337/dc19-S009 [DOI] [PubMed] [Google Scholar] 19.Gallwitz B

Nonetheless, subsequent evidence indicating that the insulinstimulating effect of GIP is partially regained through enhanced glycemic management in T2DM subjects [129, 130], coupled with the emergence of new antagonists [131] suitable for clinical investigations, is prompting a reevaluation of the involvement of GIP in moderating the DPP4i treatment glycemic effects