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Pancreatic -cells initially sense elevated extracellular glucose and allow its cellular entry through the GLUT facilitative glucose transporters [46]
Observational studies in autoimmune rheumatic diseases (ARDs) such as rheumatoid arthritis and systemic lupus erythematosus indicate similar reductions in cardiovascular events

The mitochondrial support helps maintain energy output even when caloric intake is significantly reduced

doi: 10.2337/dc21-S009 7 ZinmanBWannerCLachinJMFitchettDBluhmkiEHantelSet al
