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Description
Mechanisms by which adiponectin reverses high fat diet-induced insulin resistance in mice

Medical Condition Contrave is FDA-approved for weight management in people with a body mass index (BMI) of more than 30, or a BMI of more than 27 with another weight-related condition, like high blood pressure, Type 2 diabetes, or high cholesterol
It is an injectable drug that works by acting on two important hormones in the body GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1)

doi: 10.1016/j.amjmed.2011.08.008 4 McCoyRGVan HoutenHKZiegenfussJYShahNDWermersRASmithSA

However, the full benefits, particularly for weight loss and significant A1c reduction, can take several months to become apparent
