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For patients: Retatrutide is not currently available on the NHS or through private prescription in the UK Products sold online claiming to be retatrutide are unlicensed and potentially dangerous the MHRA advises against purchasing medicines from unregulated sources If you are interested in participating in a clinical trial, speak to your GP or specialist, who can advise on eligibility and refer you to appropriate research centres

PMCID: PMC10911117

Because GLP-1R and GIPR are central components of incretin physiology, Retatrutide allows researchers to explore how simultaneous receptor activation influences cyclic AMP signaling, hormone secretion pathways, and metabolic regulatory networks