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Table of Contents Retatrutide and Diarrhoea: What the Evidence Shows Phase 2 trial data confirm diarrhoea is a common adverse effect of retatrutide, driven largely by its GLP-1 receptor agonist component, which slows gastric emptying and alters intestinal transit
The starting daily dose for the Wegovy pill is 1.5 milligrams, which can be ramped up to the maximum dose of 25 milligrams over 90 days

Bulk retatrutide purchasing from established suppliers typically comes with quantity discounts that reflect actual savings in packaging and handling rather than quality compromises

Similar to other antidiabetic medications, such as metformin [40], and in combination with diet and exercise, the reduction in insulin resistance induced by GLP-1 RAs may help reduce or resolve AN

A separate double-blind study assessed exenatide's effect on intracranial pressure in women with idiopathic intracranial hypertension [93]
