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Moreover, this market preference also stems from its status as the only U.S.FDA-approved maintenance dose specifically indicated for long-term obesity treatment

Notably, Tirzepatide functions as a dual GIP and GLP-1 receptor agonist , with greater affinity and potency at the glucose-dependent insulinotropic polypeptide receptor ( GIPR ) compared to the glucagon-like peptide-1 receptor ( GLP-1R )

4 5 Over the past 40 years, global obesity rates have nearly tripled, according to data published by NH Phelps et al in 2024, which show that the global obesity rate among women was only 8.8% in 1990, but this figure rose to 18.5% by 2022

Most people notice appetite suppression within the first 1-2 weeks of reaching a therapeutic dose (typically 5mg)

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