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An improvement in fibrosis stage was seen in 43% of the higher dose semaglutide group versus 33% of the patients in the placebo group but this was not statistically significant

Oral GLP-1 therapy already exists, and research is expanding this category further

This cluster provides the scientific roadmap to understand and rebuild that foundation

Future studies should prioritize early PsA populations, ideally using stratified designs that incorporate metabolic profiling, to fully elucidate the dual immunomodulatory and metabolic potential of GLP-1RAs in altering disease trajectory

"Despite statements on your product labeling marketing your products for laboratory research purposes only and not for human consumption, medical use or veterinary use, evidence obtained from your website establishes that your products are intended to be drugs for human use," the agency wrote