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3 It improves endothelial function and reduces oxidative stress

Conclusion: The perioperative management of patients taking incretinbased therapies (GLP1 and GIP receptor agonists) and SGLT2 inhibitors is evolving as these drugs gain widespread use for diabetes, obesity, and cardiorenal protection

Severe caloric restriction below 1,000 to 1,200 calories daily triggers an aggressive metabolic conservation response that can halt weight loss even in the presence of a large theoretical calorie deficit

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