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The primary endpoint was to demonstrate non-inferiority (with a non-inferiority margin of 0.3%) of tirzepatide 10 mg or 15 mg, or both, compared to glargine in terms of the change in HbA1c from baseline to 52 weeks

Food intake and body weight are monitored in animals during treatment, and food consumption remains unchanged despite metabolic improvements

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doi: 10.3389/fendo.2017.00047 123 GibbsJYoungRCSmithGP

A mostly-full vial that was warm for 30 hours may still have acceptable potency for a few more doses, but do not rely on it for the remaining weeks of the expected shelf life
