glp-1 with hypothyroidism and Hypothyroidism and GLP-1: A Weight

Gastrointestinal side effects are the most commonly reported and include: Nausea (affecting 1040% of patients, depending on the specific GLP-1 agonist) Vomiting and diarrhoea (less common than nausea but can contribute to dehydration) Constipation (due to slowed gastric emptying) Abdominal discomfort or bloating These effects are typically most pronounced during treatment initiation and following dose increases

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Lancet 2021;397:971-84

The American Diabetes Association Standards of Care emphasize the importance of monitoring for adverse effects and adjusting treatment as needed to optimize tolerability while maintaining therapeutic benefit

GLP-1 receptor agonist therapy requires ongoing assessment and potential dose adjustments based on treatment response, tolerability, and evolving clinical needs