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In a 48-week phase 2 study of retatrutide involving 338 overweight or obese non-diabetic participants, researchers observed dose-dependent decreases in weight and improvements in waist circumference, blood pressure, levels of glycated hemoglobin, fasting glucose and insulin, and most lipid metrics

Firstly, it improves glycemic control by reducing HbA1c levels, thus mitigating the vascular damage caused by hyperglycemia

Moreover, tirzepatide does not appear to increase the risks of renal adverse events

What sets Ozempic ( semaglutide) apart is that it promotes weight loss without the rapid fluctuations associated with fad diets

If you are on semaglutide or tirzepatide and your current routine is mostly cardio, recalibrate now