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This systemic nature necessitates therapeutic approaches that address both hepatic and extra-hepatic metabolic abnormalities, positioning incretin-based therapies as particularly promising interventions [2]

Butand this is importantmany women have had healthy pregnancies after GLP-1 exposure, and for women with PCOS, these medications may actually improve fertility when used strategically before conception attempts

Looking toward the future The wheels of progress on multi-agonists, oral small molecules, and tissue-targeted approaches are moving forward at breakneck speed
For patients experiencing heartburn while on GLP-1 therapy, several evidence-based management strategies can provide relief without necessitating medication discontinuation