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The GLP-1 receptor agonist semaglutide reduces risks of kidney function loss, kidney failure, cardiovascular events, cardiovascular death and all-cause mortality in people with CKD and T2DM Ongoing clinical and mechanistic studies are expected to expand use of GLP-1 receptor agonists, GLP-1/GIP and other metabolic hormones for the treatment of CKD At the moment the most complete data is available for semaglutide from SUSTAIN-6 and FLOW trial which is the only trial with primary renal outcome in T2DM patients out of all GLP-1 RA Very good data for renal outcomes as secondary ones available for GLP-1 RAs dulaglutide and liraglutide and GLP-1/GIP RA tirzepatide, Very interesting and positive data from mechanistic REMODEL trial with semaglutide in T2DM patients presented but not yet published (reduced perirenal fat, rernal fibrosis and much more) Based on following excellent papers: #glp1 #gip #semaglutide #tirzepatide #liraglutide #dulaglutide #kidney #ckd #chronickidneydisease #cardiovascularcomplications

PlexusDx provides detailed guidance for safe, effective weekly injections at home

PlexusDx explains the interaction between creatine and tirzepatide, how GLP-1 receptor agonists affect muscle preservation, and what your personalized treatment plan should include

Each serving is designed to activate GLP-1a key hormone involved in appetite control and blood sugar managementmaking it the perfect addition to any wellness routine

Notably, the $500 range is also the amount manufacturers offer for self-pay obesity patients, raising important questions about whether these programs are truly benefiting those who need them most5,6