what do glp-1 drugs do Weight loss – hope or hype? GLP-1: Genetic Variants Related to

Ziyad Al-Aly

doi: 10.2337/db17-1385

GLP-1 RAs significantly reduced the risk of MACE compared with placebo (hazard ratio [HR] 0.87, 95% confidence interval [CI] 0.770.98) in HF coexisting with T2DM

GLP-1 and glucagon co-agonists Glucagon is secreted from the pancreatic a-cells and the main physiological site of action is the liver to increase hepatic glucose production [60]

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