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doi: 10.1002/epi4.13091 [DOI] [PMC free article] [PubMed] [Google Scholar] 52.Liang Y, Dor V, Rowe CC, Krishnadas N

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Calculation of HOMA-IR index The homeostatic model assessment of insulin resistance (HOMA-IR) was calculated using the formula: HOMA-IR = [fasting insulin (mU/L) fasting glucose (mg/dL)/405] 75

Evidence on B12 Supplementation During GLP-1 Therapy Clinical trials of semaglutide for weight loss (the STEP trials with over 4,500 participants) did not routinely pair semaglutide with B12 injections or measure specific B12 supplementation outcomes

The SUSTAIN-6 trial demonstrated a 26% reduction in major cardiovascular events