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doi: 10.1016/J.TINS.2018.12.007

Myofibroblasts are the primary producers of collagen in tissue fibrosis 67,68 and play a role in tissue stiffness and the development of skin and joint contractures in SSc patients

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[209].Leone-Bay A, Grant M, Greene S, Stowell G, Daniels S, Smithson A, Villanueva S, Cope S, Carrera K, Reyes S, Richardson P, Evaluation of novel particles as an inhalation system for GLP-1, Diabetes, obesity & metabolism, 11 (2009) 10501059

A meta-analysis of 30 studies on MASLD involving 3134 patients demonstrated that bariatric surgery decreased intrahepatic fat by 72 % within six months, as measured via MRI-Proton density fat fraction (MRI-PDFF) and improved histological features of MASH, including reduction in inflammation and fibrosis [197,198]