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(2) bias due to deviations from intended interventions

One key reason is that they impact a persons physiology before, during and after use

GLP-1 receptor agonists lower body weight by their influence on the central nervous system

Grading of the results The Grading of Recommendations Assessment, Development and Evaluation (GRADE) methodology was used to assess the quality of evidence for each outcome in the meta-analysis [24]

The drugs FDA-approved label indicates usage for chronic weight management for overweight or obese adults with at least one weight-related condition