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Report adverse events to FDA MedWatch at fda.gov/medwatch or 1-800-FDA-1088.

However, the evidence is mixed

Mechanistic studies reveal multi-target effects, including: 1) Metabolic regulation, 2) Anti-inflammatory action, and 3) Cartilage preservation through autophagy activation and apoptosis inhibition

However, the endogenous secretion of GLP-1 in mice is insufficient to significantly increase the number of glutamatergic neurons in this region, potentially exacerbating anxiety-like behaviors

This difference in regulation is important when deciding which treatments are safe to rely on for long-term weight management