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Compared to individual GLP- 1 receptor agonists, its action on GIP and GLP- 1 receptors improves appetite control and metabolic function, indicating higher efficacy [117]

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184 Just as intriguing, GLP-1R-mediated signaling properties of ago-allosteric modulators are not identical, thereby suggesting that such agonists could be used in order to achieve signal transduction bias

Wester A, Shang Y, Toresson Grip E, Matthews AA, Hagstrm H