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Pancreas (beta cells): Suppresses glucagon secretion, preventing the liver from releasing excess glucose
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Expect a brief adjustment period of one to two weeks
Studies in islets of phospholipase C and Epac knockout mice also suggest that Epac2 acts via Rap1-regulated phospholipase C to cause calcium-induced insulin exocytosis (Shibasaki et al., 2007
doi: 10.2337/dc23-S008
