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Newly released clinical trial data on the GLP-1 agonist drug Wegovy found that weight loss was sustained for up to four years after participants started taking the once-weekly injected medication

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The net effect is that after MBS, endogenous GLP-1 primarily acts on the brain to inhibit appetite, while only 10% of the secreted GLP-1 reaches the pancreas

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A doubleblind, parallelgroup trial was conducted in 72 adults with obesity, randomized to ...