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Only articles published in English between 1980 and 2021 were included

When and How to Increase Doses Once your body has adjusted to the initial dose, its time to consider increasing it

Potential explanations include differences in the type of patients included, adherence to study treatment, sample size, duration of drug exposure, and GLP1 receptor activation with greater HbA1c reduction with longer-acting human GLP1-based analogs than with some short-acting exendin-4 analogs
Do you need to stop your medication

doi: 10.1038/nchembio.209
