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More specifically, the ARC nucleus of the hypothalamus has been highlighted as one of the main sites mediating this action as chemical lesion of the ARC in rats ablates the anorectic action of GLP-1 (Tang-Christensen et al., 1998)

References Oral semaglutide: An OASIS from injectables. The Lancet Diabetes & Endocrinology , 2023

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Efficacy of vitamin D supplementation on glycaemic control in type 2 diabetes: an updated systematic review and meta-analysis of randomized controlled trials