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Take a look at the efficacy / safety drugs below: A 10% reduction in body weight was often cited as the threshold for widespread adoption, but these drugs seemed to still be far from it

10.1016/s0140-6736(23)01185-6
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In 2021, it gained FDA approval for chronic weight management under the name Wegovy, representing a significant advancement in obesity treatment options

[DOI] [PubMed] [Google Scholar] 37.Drucker D.J., Buse J.B., Taylor K., Kendall D.M., Trautmann M., Zhuang D., Porter L., DURATION-1 Study Group Exenatide once weekly versus twice daily for the treatment of type 2 diabetes: A randomised, open-label, non-inferiority study
