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Carolyn Bramante, who works in the weight management clinic at the University of Minnesota says she still uses metformin "quite often" for patients with a host of weight-related issues, including type 2 diabetes, pre-diabetes, and obesity, too

Key points Insulin and glucagon are the principal hormones that regulate nutrient metabolism

KARAN RAJAN: Ah, thank you so much

This interaction is particularly relevant in patients at risk for folate deficiency, such as those with malabsorption disorders, chronic alcohol use, or those taking medications that interfere with folate metabolism

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