who discovered glp-1 agonists Glucagon-like peptide-1 A Brief History of GLP-1

doi: 10.1002/oby.24336

Third, although the notion of enhancing healthspan and potentially prolonging lifespan through GLP-1 RA treatment is appealing, its application to asymptomatic individuals in clinical settings is still primarily theoretical and lacks robust empirical support at this time

The reduction in HbA 1c is independent of age (85), duration of T2D (87), or baseline HbA 1c, with meaningful reductions in all of the subgroups, even if the reduction is more significant in patients with higher HbA 1c at the baseline

Salk Institute researchers are burrowing down into the mechanistic details behind how GLP-1 drugs promote viability and stress resistance in pancreatic beta cells

Some of these medications include: Ozempic (semaglutide) Mounjaro (tirzepatide) Saxenda (liraglutide) Wegovy (semaglutide) Zepbound (tirzepatide) Saxenda, Wegovy, and Zepbound are FDA-approved for weight management, while other GLP-1 medications are used primarily for Type 2 diabetes and are sometimes prescribed off-label for weight loss