glp 1 and pregnancy JCI Insight Reconciling GLP-1s and Pancreatitis
Description
Functional fuel
This guide explores prescription options, compounded alternatives, and how genetic and biomarker factors may inform provider conversations about suitability

Several multi-targeting agonists at GIPR, GLP-1R or GCGR, developed to maximize metabolic benefits with reduced side-effects, are in clinical trials to treat type 2 diabetes and obesity

A large global retrospective cohort study (n=331,863 matched patients

Although rare, associations with nonarteritic anterior ischemic optic neuropathy, pancreatitis, medullary thyroid carcinoma, and acute kidney injury (AKI) have been reported, primarily through pharmacovigilance and case-based evidence