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Both gurmarin ( another constituent of the leaves ) and gymnemic acid have been shown to block sweet taste in humans

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The preparation method according to claim 1, wherein in step 1), the main chain is sequentially synthesized from the C end to the N end on the solid-phase synthetic resin, then the side chain protecting group of Lys is removed, and the side chain is coupled to obtain the fully-protected coupling product of the semaglutide and the solid-phase synthetic resin