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Animal studies have shown that GLP-1 activation in the brain correlates with reduced anxiety-like behaviors and improved stress resilience, suggesting a direct neurological mechanism separate from weight loss

Most people who experience shedding in this setting are dealing with a pattern that is common, explainable, and often temporary

Regulatory momentum: U.S

When you lose 10 pounds of muscle because your GLP-1 stripped it away and you didn't do anything to stop it, your resting metabolism drops by roughly 60 to 70 calories per day

Stopping treatment can change appetite and weight trajectories, but outcomes vary and depend on long-term habits, follow-up, and individualized plans