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Exercise considerations Exercise during semaglutide therapy preserves lean muscle mass, which is critical during rapid weight loss

[DOI] [PubMed] [Google Scholar] 9.Trujillo JM, Nuffer W, Smith BA

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They include pain or redness at the injection site, slight swelling or tenderness, mild diarrhea, and sometimes itching or a generalized feeling of body swelling

While some individuals may begin to notice initial changes, such as reduced appetite or early weight loss, within a few weeks, more significant results typically take longer