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Insulin resistance and chronic hyperglycemia cause a cascade of pathological events in the brain, including neuroinflammation, impaired neurotransmitter systems and energy metabolism, oxidative stress, and vascular pathologies that ultimately lead to neurodegeneration, loss of synaptic plasticity, brain aging, cognitive impairment, and dementia

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Akkermansia muciniphila produces P9, a small protein that interacts with ICAM-2 to increase thermogenesis and glucagon-like peptide-1 (GLP-1) secretion in mice

Taking a look at the company behind Ozempic and Wegovy and diving into their history, business, and the challenges it now faces

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