glp 1 analogue mode of action GLP-1 Receptor Agonists as Treatments for Type 2 Diabetes Emerging Frontiers in GLP-1 Therapeutics:

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However, an increasing number of research studies are demonstrating that these substances also have neuroprotective effects in neurodegenerative diseases, mental disorders, and other brain conditions

Among people with pre-existing SUDs, initiation of GLP-1 receptor agonists was associated with reduced risk of SUD related emergency department visits (0.69 (0.61 to 0.78), NRD 8.92 (11.59 to 6.25)), SUD related hospital admissions (0.74 (0.65 to 0.85), NRD 6.23 (8.73 to 3.74)), and SUD related mortality (0.50 (0.32 to 0.79), NRD 1.52 (2.32 to 0.72)), and drug overdose (0.61 (0.42 to 0.88), NRD 1.49 (2.43 to 0.55)) and suicidal ideation or attempt (0.75 (0.67 to 0.83), NRD 9.95 (13.14 to 6.77))

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