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For the meta-analysis (which used both patient-level and trial-level data), HRs (active comparator: placebo) and 95% CIs for CV outcomes were estimated using a Cox proportional hazards model

There are a number of reasons you might struggle to lose weight beyond just diet and exercise

For Mounjaro-related adverse effects, the appropriate external cause code is Y42.3 (Insulin and oral hypoglycaemic [antidiabetic] drugs causing adverse effects in therapeutic use)

The semaglutide meta-analysis found a 31% reduction in atrial fibrillation, a condition that itself causes blood clots in the heart that can travel to the brain and cause stroke

the 2023 SELECT trial), have fueled surging global demand