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281 Clinical evidence further indicates organ-specific anti-aging effects: semaglutide treatment in individuals with HIV-associated lipohypertrophy resulted in an approximate 3.1-year reduction in biological age, primarily through improvements in the immune/inflammatory system and the brain

The first GLP-1 receptor agonist, exenatide was approved by the FDA for the treatment of T2DM in 2005

[DOI] [PMC free article] [PubMed] [Google Scholar] 100.Lu Y, Wu L, Lin M, Bao X, Zhong H, Ke P, et al

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This law dates back to 2003, around the time of the fen-phen scandal, when it was found to cause serious heart problems