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Notably, this reduction in LDL-C is dose-related

Main text Modern GLP-1 receptor agonists and co-agonists (GLP-1 medicines) such as liraglutide, dulaglutide semaglutide, and the GLP-1R/glucose dependent insulinotropic polypeptide receptor (GIPR) co-agonist tirzepatide, were initially developed for the treatment of type 2 diabetes (T2D) due to their actions to increase insulin and decrease glucagon secretion and slow gastric emptying through effects on the pancreas and brain

The medication was generally well-tolerated

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