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In addition, the inhibitory effect of intragastric nutrient infusion on food-motivated behaviors may operate via sex-specific pathways as ip injection of the GLP-1R antagonist exendin-9 prevents the reduction in operant responding following nutrient infusion in male but not female rats [92]
Since GLP-1 receptor agonists mute hunger, taking it away frequently leaves hunger knocking at the door, occasionally more aggressively than before
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