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In a study using cultured rat hippocampal neurons, pre-treatment of nerve cells with GLP-1 resulted in a weakened Ca 2+ response to glutamate and weakened membrane depolarization ( Effects on Parkinsons Disease Parkinsons disease (PD) is a chronic neurodegenerative disease that affects the central nervous system and the second most common neurodegenerative disease after AD (56)

In both my clinical experience and evidence in published studies, it is clear that many people discontinue GLP-1 treatment because of side effects, said Noom Chief Medical Officer Dr