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Finally, we presented our insights on clinical concerns such as appropriate trial endpoints, management of comorbidities, and future developments
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According to the 2024 World Obesity Report, the global prevalence of obesity is steadily increasing, with projections indicating that by 2035, over half of the world's population will be classified as overweight [1]

P=0.001] and whole-body bone mineral density [MD0.02 kg/m2 (95% CI,0.04 to0.00)
