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Retatrutida is a new-generation investigational peptide that acts as a triple agonist for GLP-1, GIP and glucagon receptors

Clinical trials show average total body weight loss of 14.9% over 68 weeks, with some patients achieving 20% or more

Additionally, interindividual variability in pharmacologic response, baseline eating patterns, and metabolic factors influence treatment response

Thanks to its FDA approval, tirzepatide offers a scientifically validated approach to weight loss that targets appetite regulation and insulin sensitivity